What is the maximum binding capacity for proteins on the MaxiSorp surface and the PolySorp surface?
Molecules bind to the PolySorp and MaxiSorp surfaces through passive adsorption. Using IgG as a reference molecule and knowing that it is a globular molecule, theoretical calculations indicate that the maximum binding for the MaxiSorp surface, in monolayer, is 650 ng/cm². For the PolySorp surface, the binding capacity is 220 ng/cm². A detailed discussion of the principles and calculations is presented in Nunc Bulletin No. 6. See Nunc Bulletin No. 6.
