What is the matching strand of mRNA to the following DNA strand: AAACCGTTGACTT?
DNA 5′-AAACCGTTGACTT-3′ RNA 3′-UUUGGCAACUGAA-5′ DNA and RNA sequences are always written in the 5′->3′ direction. So if transcription was happening using that AAACCGTT sequence as template, the RNA made would be 5’AAGUCAACGGUUU-3′ If it was made using the opposite strand as a template, then the mRNA would be the same as the given DNA, but the T’s would be changed to U’s. If you look at what real biologists do, they would list the gene as AACCGTTGACTT, and the RNA would be AACCGUUGACUU, because it’s just simpler that way. But real biologists aren’t trying to prove to their teachers that they understand base pairing rules, but you are, so to be clear, you may want to write out what I wrote out at the very top, with the 5′ and 3′ labeling, and then your teacher will know that you understand the lesson.
