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What is the mass sensitivity of Q-Sense instruments?

April 26, 2017instruments mass q-sense

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What is the mass sensitivity of Q-Sense instruments?

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The maximum mass sensitivity in liquid is about 0.5 ng/cm2 for Q-Sense E4 and 1 ng/cm2 for Q-Sense D300 if measuring at a rate of 1 data point / 5 seconds. Q-Sense E4 operating at all four sensors and at 3 harmonics has a sensitivity of about 2 ng/cm2 if all data are collected in 1 second. For example, consider a monolayer (<100% surface coverage) of Myoglobin (17800 Da): the monolayer corresponds to 177 ng/cm2 (change in frequency, 10 Hz).