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What is the major difference between thalassemia and sickle cell anemia?

anemia CELL Sickle thalassemia
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What is the major difference between thalassemia and sickle cell anemia?

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Thalassemia is a quantitative problem of too few globins synthesized, whereas sickle-cell anemia (a hemoglobinopathy) is a qualitative problem of synthesis of an incorrectly functioning globin.

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