What is the main difference between a valve and a transistor amplifier?
The weight! All kidding aside, there are two different construction philosofies, that have very recognizable sounds. Many transistor amplifiers offer important characteristics in terms of sound quality, especially with the advent of sound emulation circuits, but also some battle horses of the past, like the Jazz Chorus series by Roland, have been (and are) great amplifiers. The valve amplifier certainly has a warmer and more full sound, but what counts is your own personal taste. You can find all the information in the amplification section.