What is The Jackson Laboratorys Position on Use-Licenses for Mouse Strains?
The Jackson Laboratory makes every effort to accept and distribute mouse strains that are unencumbered by license restrictions. However, some institutions that create genetically engineered strains or that have developed patented technology that is used to create genetically engineered mice require that users obtain use-licenses. To expedite distribution of new strains, we request that users work directly with the institutions requiring licenses to obtain user licenses. Specific patented technologies requiring licenses include the following: • “OncoMouse™” Technology (E.I. duPont de Nemours and Company) • “Cre-lox” Technology (DuPont Pharmaceuticals Company) • “TET-System” Technology (TET Systems Holding). We also supply M.I.T. originated p53 “knockout” mice (Trp53tm1Tyj), which require: 1) a license from Taconic Farms, which has licensed the Baylor College of Medicine patent (Donehower); and 2) a license from E.I. duPont de Neumors and Company for use of OncoMouse™ Technology. For mor
