What is the incidence of vaccine associated paralytic polio (VAPP) in the developing world?
The overall risk of VAPP in developing countries has been estimated to fall in the range of 1 case per 1.5 million doses administered (Latin America) to 1 case per 4.6 million doses administered (India). These are the only two developing countries/regions with published studies on this topic. Work is currently in progress to estimate risk of VAPP per million birth cohort, which will provide numbers that are potentially more useful to policy-makers in the future.