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What is the importance of sub-populations in estimating sensitivity and specificity of a diagnostic test?

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What is the importance of sub-populations in estimating sensitivity and specificity of a diagnostic test?

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From Sally Hollis {There is a brief discussion of this in the explanation and elaboration document for the STARD statement (see items 23 and 18) web references: STARD initiative http://www.consort-statement.org/stardstatement.htm Explanatory document http://www.clinchem.org/cgi/content/full/49/1/7}

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