What is the Genome@home project and how does it relate to the Folding@home project?
Genome@home was another distributed computing project from the Pande Group Lab. As of April 15, 2004, the project has concluded. You can find more details at http://genomeathome.stanford.edu The goal of Genome@home is protein design and its applications. One central application of ours for protein design is the creation of large libraries of designed protein sequences, in a sense “redesigning” or “reverse-engineering” an existing Genome (hence the name “Genome@home”). Another application of protein design is to understand why proteins fold and why they misfold and aggregate. This is a central question of Folding@home and directly relates to our study of protein folding and misfolding, as it is related to misfolding-related diseases, such as Alzheimer’s, ALS, etc.
