What is the function of vaults?
The precise function of vaults is still unknown. Their size, shape and localization to nuclear pores suggests that they may be a plug of the pore complex. Their hollow interior and role in multidrug resistance indicates that they may be carriers. The fact that one of the high molecular weight vault proteins (p240 or TEP1) is a component of telomerase may indicate a role in RNP assembly, transport or regulation.