What is the function of the smooth and rough endoplasmic riticulum?
Rough endoplasmic reticulum The surface of the rough endoplasmic reticulum is studded with protein-manufacturing ribosomes giving it a “rough” appearance (hence its name).[3] But it should be noted that these ribosomes are not resident of the endoplasmic reticulum initially. The ribosomes only bind to the ER once it begins to synthesize a protein destined for sorting.[4] The free ribosome begins producing the polypeptide until a cytosolic signal recognition particle recognizes the pre-piece of 5-15 hydrophobic amino acids preceded by a positively charged (basic) amino acid. This makes it easy for the complex to loop the sequence through the hydrophobic membrane. The pre-piece is then cleaved off. Smooth endoplasmic reticulum The smooth endoplasmic reticulum has functions in several metabolic processes, including synthesis of lipids and steroids, metabolism of carbohydrates, regulation of calcium concentration, drug detoxification, attachment of receptors on cell membrane proteins, and
