What is the formulation for UNC Hospitals Mucositis Mixture, also known as “Sleepy Butter”?
UNC Hospitals Mucositis Mixture has been officially added to the UNC formulary. The approved recipe by the Pharmacy and Therapeutics Committee is: -Diphenhydramine liquid 2.5 mg/mL -Maalox suspension (or formulary equivalent) -Lidocaine, viscous 2% Admix equal volumes of the three ingredients. UNC usually dispenses 300 mL total volume (6 month expiration). Recently, UNC discovered a prescription product from CutisPharma, which is a similar formula, but available in a kit (First™ Mouthwash BLM (NDC 65628-050-01)). The kit includes a 236 mL bottle of aluminum hydroxide/magnesium hydroxide/simethicone suspension with two separate bottles, one containing diphenhydramine 0.2 g powder, and the other containing lidocaine hydrochloride powder 1.6 g. The pharmacist can combine the dry powders into the suspension.
