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What is the explanation for the term Minimal Residual Disease (MRD)?

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What is the explanation for the term Minimal Residual Disease (MRD)?

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MRD describes a certain stage of a tumoral disease characterized by disseminated tumor cells remaining in the patient’s body after surgical resection or chemo-/radiotherapy of a primary tumor. Very often these remaining cells are resistant against the therapy and potentially can cause metastases.

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