What is the effect on different molecules using supersonic expansion shockwaves?
Any aerosolization process will impart some energy onto the molecules being aerosolized. The good news is that the Sonik LDI Aerosolization Technology is actually quite benign. We have tested a broad range of molecules using pH, mass spectroscopy, mass balance, and ELISA plate binding techniques and have never shown any significant disruption of any molecules. In fact, we have even aerosolized liposomes, which are held together by ionic bonding, and demonstrated the ability of the Sonik LDI system to keep them intact. Q: When do you apply this technology to new molecules under development? A: Because the Sonik LDI Aerosolization Technology is simpler and more straightforward than many of the other existing pulmonary delivery systems, it can be integrated with the development of a new molecule at the early stages of proof-of-concept and preclinical work. Doing so can be of tremendous benefit to the biotech firm as well as to the large pharmaceutical company. The biotech company benefits
