What is the dosage of dDAVP?
The dose of dDAVP required to control CDI does vary with the size of the patient. However, it cannot be specified exactly in terms of body weight because other factors, such as differences in absorption or metabolism, also exert a major influence. Therefore, the optimum dose varies quite widely from patient to patient and must be determined by trial and error. The dose also depends on the route of administration. When given by injection, it is usually necessary to give between 1 microgram to 2 micrograms once or twice a day. By nasal spray, the necessary dose can range from 5 micrograms to 20 micrograms twice or three times a day. By tablet, the usual dose is 100 micrograms to 200 micrograms two to three times a day.