What is the difference between Trana Discovery technology and RNA interference or RNAi?
Basically, Trana Discovery is developing drug discovery assays to identify small molecule compounds that disrupt the use of specific tRNAs by disease-causing microorganisms. While one of the respective assay components is a short oligonucleotide, which is a synthetic mimic of a portion of the anti-codon stem loop of the selected tRNA, compounds discovered by this process for eventual development as new drugs are easy-to-administer small molecules.
