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What is the difference between TPA and RefSeq?

refseq TPA
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What is the difference between TPA and RefSeq?

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Both TPA and RefSeq sequences are derived from primary sequence data found in the DDBJ/EMBL/GenBank International Nucleotide Sequence Collaboration Databases. However, while RefSeq annotation is based on additional information available in the literature and/or an automated computation method, TPA annotation must be supported, directly or indirectly, with experimental evidence by the submitter.

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