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What is the difference between the management of drug resistant TB and drug susceptible TB?

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What is the difference between the management of drug resistant TB and drug susceptible TB?

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In areas of minimal or no drug resistance DOTS achieves cure rates of up to 95%; rates high enough to dramatically reduce the TB burden while preventing the emergence of drug resistant TB. However unlike drug susceptible TB that has a solid, effective management strategy, management of drug resistant TB is still in a pilot stage. While the former can be cured within 6 months, forms of drug resistant TB requires, extensive chemotherapy (that is more toxic) for up to two years.

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