What is the difference between the BeadStudio Genotyping Module and the BeadStudio LOH Plus Module?
The BeadStudio Genotyping module is designed for analyzing GoldenGate and Infinium project data sets. The Genotyping Module allows you to normalize raw data, generate genotype calls, perform clustering, analyze data intensity, and calculate LOH (Loss of Heterozygosity) and CN (Copy Number) scores. Advanced, flexible graphical tools enable the visualization of potential regions of LOH along different chromosomes. The BeadStudio LOH Plus module is designed specifically to study chromosomal aberrations and allelic imbalances. Key features of this module include paired-sample analysis where one sample serves as a reference, auto-detection of chromosomal aberrations, customized bookmarking of genomic regions of interest, and a chromosomal heat map that can be used to examine LOH/CN-related intensity differences along chromosomes.
