What is the difference between SBIs pFIV lentiviral-based cloning and expression vectors and other viral-based vectors?
The difference between lentiviral-based vectors and adenoviral vectors Like lentiviral-based vectors, adenoviral vectors can be packaged into viral particles when expressed cells expressing the appropriate genetic elements, and like lentiviral particles, adenoviral particles will infect a wide range of cells, including non-dividing and dividing cells. However, once introduced into target cells, adenoviral expression is very high and often has toxic effects on the cell. Obviously, this type of system is not suitable for gene function analysis since it would not be clear whether observed effects are a result of the expressed sequence or side effects of over expression. The difference between lentiviral-based vectors and other retroviral-based vectors SBIs pFIV lentiviral system is based on the feline immunodeficiency (FIV) virus and the pFIV vectors, when packaged into VSV-G pseudotyped viral particles, effectively transduce both dividing and non-dividing cells. Most other commercial ret
