What is the difference between marrow and PBSC donation?
Unlike marrow donation, PBSC donation is a non-surgical procedure, and does not require anesthesia. Marrow donors may experience pain and residual stiffness up to a few weeks after the procedure. PBSC donors experience symptoms such as bone pain and muscle pain prior to the donation while receiving filgrastim (also referred to as G-CSF), the drug used to increase the release of blood-forming cells from the bone marrow, but these symptoms go away within 24 hours of donation.
