What is the difference between IgE-mediated and non-IgE-mediated food allergies?
IgE-mediated food allergies involve the production of IgE antibodies to certain foods that usually occurs immediately after the ingestion of the suspect food. These are defined as immediate food allergies because symptoms generally manifest within 2-3 hours after consumption of the culpable food. A late phase response peaks at about 12-24 hours post contact and may last up to 48 hours.