What is the difference between Great Wonders and Small Wonders?
Both types of wonders give benefits to the civilization(s) that build them – the only difference is who can build them. Great Wonders can only be built once, by one civilization, and only they get the benefit of that wonder. If that wonder is razed, no other civilization can ever build it again; it is lost forever. However, Small Wonders can be built by each civilization – so every civilization can get the benefit of that wonder if they build it. For example, the Apollo Program is a Small Wonder, and can be built by each civilization, as it is needed to win the Space Race, although, say, the Sistine Chapel is a Great Wonder, and can only be constructed by a single civilization.