What is the difference between Effexor and Wellbutrin?
I am switching to Wellbutrin after Effexor has been ineffective; my pharmicist said that they work on different receptors (serotonin and norepinephrin vs dopamine). How else are they different? If the Effexor didn’t work, but the Wellbutrin does, does that mean that my depression is being caused by a deficiency in dopamine? A: Effexor is a SNRI (Serotonin/Norepinephrine Reuptake inhibitor) Wellbutrin is a DNRI (Dopamine/Norepinephrine Reuptake Inhibitor) Rather than a deficiency, view it as though the neurotransmitters are being used up too fast or not staying in place long enough. The medication keeps them in place longer & staying between the synapses (spaces) between neurons (the cells that transmit & receive the neurotransmitters). In depression that’s where the chemical “fall aside vs. reaching the next neuron. So, according to your question, it would mean your depression is being caused by a misfiring of dopamine & norepinephrine. However, the choice of medications is not that si