What is the difference between an Albumin:Creatinine (ACR) or Protein:Creatinine ratio (PCR)??
Urinary dipsticks are not good at detecting small quantities of protein (microalbuminuria – equivalent to 0.15g/day) yet it is known to predict the development of overt diabetic nephropathy and adverse outcomes in diabetics. Thus guidelines suggest testing for the specific protein albumin, using the more sensitive ACR, yearly in diabetics even if dipstick protein is negative to identify those at high risk. If dipsticks show >=1+ of proteinuria or ACR is >30 then generally a PCR should be used.
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- What is the difference between an Albumin:Creatinine (ACR) or Protein:Creatinine ratio (PCR)??
