What is the depth of penetration of halide light compared to laser scanning?
Neither Hg/halide light or laser scanning impact depth of penetration. Both have a penetration of about 30–100 µm. To penetrate deeper, use multiphoton confocal imaging, which uses high wavelength (700–1200 nm) lasers that can penetrate to about 100–200 nm. Note that wavelength of light and opacity of tissue impact depth of penetration. The higher the wavelength, the deeper the penetration.