What is the definition of BSL3+ containment?
Unlike BSL2+ containment, BSL3+ is not defined in the NIH Guidelines for Research Involving Recombinant DNA Molecules (NIH Guidelines) or Biosafety in Microbiological and Biomedical Laboratories (BMBL). While BSL3+ is a commonly used term, only BSL3 containment is described in the NIH Guidelines and BMBL. Depending on the nature of the research, IBCs may recommend BSL3 containment with appropriate enhancements (e.g., BL3 with respiratory protection, HEPA filtration, shower out, etc.).
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