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What is the definition of a dominant exposure pathway in a multipathway cancer risk assessment?

April 26, 2017assessment cancer definition exposure Pathway risk

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What is the definition of a dominant exposure pathway in a multipathway cancer risk assessment?

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Dominant exposure pathways are defined as the two exposure pathways that have the largest contribution to the cancer risk estimate when using high-end point-estimates for all applicable exposure pathways. The determination of dominant pathways is substance-specific.