What is the current philosophy on the use of mitomycin-c in a trabeculectomy?
The current philosophy varies considerably. I use mitomycin on patients with advanced damage, as well as on those who have had previous surgery, have inflammation, are African American or Hispanic, or are so young that scarring and excessive healing seem likely. For all others I use a 5-FU soak at the time of surgery. The soak of both mitomycin and 5-FU is varied according to the perceived risk involved. Dr.
