What is the current immune suppression protocol used?
The most common combination used is tacrolimus (Prograf®) and mycophenolate mofetil (Cellcept®) as these agents are much better tolerated than the original Edmonton protocol. Induction protocols vary. Choices are tailored to the individual. At any time, we may have clinical trials underway to assist researchers with determining whether new or existing therapies provide benefit to Clinical Islet Transplant patients. Patients must be consented for enrollment in clinical trials and only those meeting the inclusion criteria will be approached. Working towards a protocol that doesn’t need lifelong immunosuppression is an important goal for all of us in the field.