What is the CRS (Cambridge Reference Sequence)?
The CRS is the Cambridge Reference Sequence. It was the first mtDNA sequence to be completed, and all mtDNA tests are now compared to a revised edition of it. The entire sequence is very long, and if written out completely would be a series of letter combinations that would be much longer than this example: ATCGATCGGCTAATTACGCGATATATATACGACG. Instead, we create a list of the places where your sequence is different from the CRS. If two individuals have the same list of differences from the CRS, they have the same sequence as one another in the region(s) tested. For your benefit, the CRS for the HVR1 and HVR2 regions is listed at the bottom of your mtDNA Results section.
The CRS is the Cambridge Reference Sequence. It was the first mtDNA sequence to be completed, and all mtDNA tests are now compared to a revised edition of it. (rCRS) The entire sequence is very long, and if written out completely would be a series of letter combinations that would be much longer than this example: ATCGATCGGCTAATTACGCGATATATATACGACG. Instead, we create a list of the places where your sequence is different from the rCRS. If two individuals have the same list of differences from the rCRS, they have the same sequence as one another in the region(s) tested. For your benefit, the rCRS for the HVR1 and HVR2 regions is listed at the bottom of your mtDNA Results section.
