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What is the connection between HER-2 status and the selection of adriamycin-based therapy?

April 26, 2017connection her-2 selection Status therapy

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What is the connection between HER-2 status and the selection of adriamycin-based therapy?

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An interaction between HER-2 amplification and response to adriamycin-based therapies has been demonstrated. Specifically, HER-2 amplification is associated with improved response to intensified adriamycin-based chemotherapies. Clinical trials demonstrate that patients with HER-2 amplification may benefit from dose intensive adriamycin-based therapy based on disease-free and overall survival.