What is the composition of Pandemrix suspension and emulsion for emulsion for injection Pandemic Influenza vaccine (H1N1)v (split virion, inactivated, adjuvanted)?
The active substance of Pandemrix Pandemic Influenza vaccine (H1N1)v is split influenza virus, inactivated, containing antigen propagated in eggs from healthy chicken flocks equivalent to: A/California/7/2009 (H1N1)v-like virus: 3.75 micrograms haemagglutinin per 0.5 mL dose. The vaccine is formulated with thiomersal as a preservative. The vaccine also contains GSK’s proprietary AS03 Adjuvant System to stimulate a better immune response. The main components of the adjuvant are squalene, DL-α-tocopherol and polysorbate 80. Pandemrix Pandemic Influenza vaccine (H1N1)v will consist of two vials – one containing pandemic (H1N1)v 2009 antigen and the second, GSK’s AS03 adjuvant system. Contents of the two vials will be combined before administration. Once the two components (the antigen and the adjuvant) are mixed, the vaccine should be used within 24 hours.
Related Questions
- What is the difference between the seasonal influenza vaccine and the pandemic vaccine against influenza A (H1N1)v?
- What is the indication for Pandemrix Pandemic Influenza vaccine (H1N1)v (split virion, inactivated, adjuvanted)?
- If the (H1N1)v strain mutates, will Pandemrix Pandemic Influenza vaccine (H1N1)vstill be effective?
