What is the comparative effectiveness of Newer Antiemetics in treating or preventing nausea and/or vomiting?
There were very few differences between granisetron and ondansetron, regardless of chemotherapy regimen, antiemetic regimen, use of concomitant corticosteroid therapy, patient population, or outcome reporting method.21, 22, 25–28, 33, 36–40, 42, 45–47, 49–52 Dosage levels ranged widely for both granisetron (po 1 and 2 mg; iv 10 mcg/kg and 3 mg) and ondansetron (iv 2–32 mg). Dosage level inequities between treatment groups also did not seem to have an impact on comparative efficacy.
