What is the chance that an Rh (D) negative woman will carry an Rh (D) positive fetus?
Approximately 17% of Caucasian women and men will be Rh (D) negative. • This means that approximately 1 in 6 Rh (D) negative women will have a partner who is also Rh (D) negative. If both the mother and the father of the baby are Rh (D) negative, the fetus will always be Rh (D) negative. • Approximately 5 in 6 Rh (D) negative women will have a partner who is Rh (D) positive. Of these, approximately 45% of the fathers will be homozygous for the Rh (D) antigen and 55% will be heterozygous for the Rh (D) antigen. • If the father of the baby is Rh (D) positive and homozygous for the Rh (D) antigen, the fetus will always be Rh (D) positive. • If the father of the baby is Rh (D) positive and heterozygous for the Rh (D) antigen, the fetus will have a 50% chance of being Rh (D) negative and a 50% chance of being Rh (D) positive. These figures are correct as long as paternity can be assumed. In cases of non-paternity, the risk will depend on the rhesus genotype of the biological father. Informa