What is the chance of having a second child with a Chromosome 15q Duplication?
The answer to this question depends primarily on the results of chromosome and / or FISH studies in the parents of the child with the chromosome 15q duplication. Usually, dup15q occurs in a child ‘out of the blue’, with no previous family history of the condition. Most often, genetic blood tests on the child’s parents do not show any unusual arrangement of their chromosomes which would have predisposed them to having a child with dup15q. In such cases, the occurrence of dup15q is considered to be ‘sporadic’, and the child’s parents are not at increased risk over anyone else in the general population for having a second child with dup15q.
