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What is the CA-125 tumor marker?

April 26, 2017CA-125 Marker tumor

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What is the CA-125 tumor marker?

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This is a substance that is made by ovarian epithelial cancer cells and can be measured in the blood. Eighty percent of advanced ovarian cancers will have an elevated CA-125. Other conditions, including endometriosis, menstruation, pregnancy, and liver disease, can also elevate the CA-125. Also, it can be elevated in other non-ovarian cancers, such as breast, lung, and colon cancer. Measurements of the CA-125 are especially useful in monitoring the response of a known ovarian cancer to therapy. An ovarian cancer that is responding or shrinking due to chemotherapy will have a dropping CA-125. A cancer that is progressing or growing will have a rising CA-125.