What is the best way to treat the amenorrhoea in women receiving Depo-Provera?
Counselling and reassurance before administration of the first dose is essential. In the first year of Depo-Provera use 30-50% will develop amenorrhoea; in the second year amenorrhoea occurs in 70%. If this is a concern for a woman a course of oral estrogen for 14-21 days will often induce regular withdrawal bleeds again.
