What is the best joint supplement for a horse with arthritis?
In independent research, meaning it is not sponsored by the companies that profit from selling supplements, orally fed MSM has been shown to be effective and safe. Oral chondroitin sulfate has been shown to have very low to no bioavailability, meaning it is poorly absorbed, and the molecules are too large so that what does get out of the GI tract never reaches the joints to do any good. Orally fed glucosamine hydrochloride (hcl) has been shown to only have about 8% bioavailability, meaning that very little of what is fed is actually used by the joints, whereas glucosamine sulfate has a high bioavailability at about 97 to 98%. So, MSM and glucosamine sulfate both have been shown to reach the joints in sufficient dosage to exert a beneficial effect. Adequan is FDA approved and can be injected IM, and has been proven to be highly effective for joint support. FDA approval assures that there have been extensive clinical trials and rigid controls, with verification of safety and efficacy of
