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What is the basis of drug regimens?

April 26, 2017basis drug regimens

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What is the basis of drug regimens?

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Ans: Drug regimens are decided in consideration of the following facts: Mode of action of individual drugs The dose of each drug depends on minimum inhibitory concentration (MIC) i.e. the minimum drug concentration that inhibits bacterial growth in-vitro, and Minimum Bactericidal Concentration (MBC) i.e. the concentration at which bacteria are killed. MBC is usually higher than MIC. Prevention of drug resistance. Demonstration of efficacy during drug trials and field trials in terms of sputum conversion and relapse. Minimal side effects. Cost effectiveness. Operational feasibility.