What is the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study?
From 1985 to 1993, the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study in Finland studied a group of 29,133 male smokers between the ages of 50 and 69 years to determine whether daily supplementation with alpha-tocopherol, beta-carotene, or both, would reduce the number of lung or other cancers (10). After the original trial period ended, researchers continued to follow the participants. • What is the link between H. pylori and gastric cancer, according to the ATBC follow-up study? Through April 1999, the Finnish Cancer Registry diagnosed 234 participants of the ATBC study with gastric cancer. Each of these participants was randomly matched by age with a cancer-free control participant. H. pylori infection status was determined from blood samples initially obtained from each study participant at the time of enrollment in the study. Comparing cancer subjects with non-cancer controls, the ATBC gastric cancer follow-up study concluded that infection with H. pylori was a str