What is Stealth™ RNAi?
Stealth™RNAi is the next generation in RNAi chemistry. Stealth™ RNAi molecules are 25mer, blunt-ended duplexes with proprietary chemical modifications. These chemical modifications were specifically designed to eliminate the induction of cellular stress response. They also make Stealth™ RNAi more stable than standard siRNA in serum and reduce the possibility of off-target effects by ensuring that only the antisense strand of the Stealth™ duplex enters the RNAi pathway.