What is spinal and bulbar muscular atrophy?
Spinal and bulbar muscular atrophy is a disorder of specialized nerve cells that control muscle movement (motor neurons). This condition, which mainly affects males, is characterized by muscle weakness and wasting (atrophy) that usually begins in adulthood and worsens slowly over time. Muscle wasting in the arms and legs results in cramping, difficulty walking, and a tendency to fall. Certain muscles in the face and throat (bulbar muscles) are also affected, which causes progressive problems with swallowing and speech. Additionally, muscle twitches (fasciculations) are common. Some men with the disorder experience unusual breast development (gynecomastia) and may be unable to father a child (infertile).
