What is SOD used for?
Anti-inflammatory White blood cells involved in the acute inflammatory response release large amounts of superoxide, which appears to contribute to the destruction of bacteria. Similarly, the amount of superoxide released at the site of an inflamed joint has been shown to cause extensive and rapid degradation of synovial fluid. SOD generally protects the fluid against this degradation. Furthermore, it protects the leucocytes themselves from free radical damage. Although IV infusion of SOD has little anti-inflammatory activity because of its rapid renal clearance, the local injection of SOD has proven to be an effective treatment for a variety of inflammatory disorders. Superoxide has been successfully used to treat human inflammatory diseases. In West Germany, where orgotein has been in general medical use for years, the drug is injected locally for the management of osteoarthritis, sports injuries, and knee joint osteoarthritis. SOD has been used for the treatment of soft tissue infla
