What is Single upper central incisor?
• Single upper central incisor: A very rare syndrome characterized by various defects in the middle of the face. Single upper central incisor is listed as a “rare disease” by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Single upper central incisor, or a subtype of Single upper central incisor, affects less than 200,000 people in the US population. Source – National Institutes of Health (NIH) Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Single upper central incisor as a “rare disease”.