What is Sigmas Seppro® line of immunoaffinity separation reagents for proteomics sample processing, and how do they compare to the competition?
We think that Seppro® is the ultimate application for IgY antibodies, playing directly to their technical strengths. Sigma has a patented technology to covalently link in an oriented fashion “affi-pure” IgYs directed against abundant plasma/serum proteins on the surface of microbeads specifically designed for IP applications. While antigen binding and specificity is quantitatively higher than the goat IgG-based solutions offered by our competitors, Seppro® is qualitatively better for separating non-human mammalian antigens such as albumin, fibrinogen and transferrin from rat, mouse, or dog sera. This enables highly efficient toxicoproteomics & biomarker discovery, and confirmation of animal disease models.
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