What is Sigmas Seppro line of immunoaffinity separation reagents for proteomics sample processing, and how do they compare to the competition?
We think that Seppro is the ultimate application for IgY antibodies, playing directly to their technical strengths. Sigma has a patented technology to covalently link in an oriented fashion “affi-pure” IgYs directed against abundant plasma/serum proteins on the surface of microbeads specifically designed for IP applications. While antigen binding and specificity is quantitatively higher than the goat IgG-based solutions offered by our competitors, Seppro is qualitatively better for separating non-human mammalian antigens such as albumin, fibrinogen and transferrin from rat, mouse, or dog sera. This enables highly efficient toxicoproteomics & biomarker discovery, and confirmation of animal disease models.
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