What is retinoic acid and why do you add it to the nighttime minoxidil solutions?
A. Retinoic acid (tretinoin or all-trans-retinoic acid) has been used for many decades as Retin-A in the treatment of acne. More recently it is being advocated to remove wrinkles due to sun damage and aging. It works essentially as a chemical peel and as a biologic response modifier. It allows for better penetration of the minoxidil and promotes epithelial cell growth.blue_top.