What is PRA?
A PRA test can be performed many different ways. Basically, we take known HLA proteins and react them with a patient’s serum. If the patient has antibodies to a particular HLA protein, the antibodies will bind. We then add other special proteins to allow us to detect that the antibody is bound to the HLA protein. By determining which HLA proteins a patient reacts to, we can determine if a potential patient/donor combination is likely to have a good or bad outcome.