What is polyarteritis nodosa?
Polyarteritis nodosa is a rare autoimmune disease (immune system attacking its own body) featuring spontaneous inflammation of the arteries (arteritis). Because arteries are involved, the disease can affect any organ of the body. The most common areas of involvement include the muscles, joints, intestines (bowels), nerves, kidneys, and skin. Poor function or pain in any of these organs can be a symptom. Poor blood supply to the bowels can cause abdominal pain, local bowel death, and bleeding. Fatigue, weight loss, and fever are common. Polyarteritis nodosa is most common in middle-age people. Its cause is unknown, but it has been reported after hepatitis B infection. Polyarteritis is not felt to be an inherited condition. How is polyarteritis nodosa diagnosed? The diagnosis is supported by tests that indicate inflammation including elevation of blood sedimentation rate and C-reactive protein. The white blood cell count and platelet count can be elevated, while the red blood count is de
